Xanthocillin X dimethyl ether (XDE) is an isonitrile-containing metabolite isolated from the mycelia of Aspergillus sp. first reported by Chugai Pharmaceutical Co., Japan in 1968. XDE is active against Newcastle disease, vaccinia and herpes simplex viruses, and inhibits the growth of Bacillus subtilis. XDE is a thrombopoietin receptor agonist. XDE was patented as an antitumor agent in 1992. Source: Aspergillus sp. Synonyms: XDE, Xanthocillin X dimethyl ether, Xanthocillin X permethyl ether CAS No: 4464-33-9 Molecular Formula: C20H16N2O2 Molecular Weight: 316.4 Appearance: Off-white solid Solubility: Methanol, DMSO. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with methanol or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight:
316.4
CAS Number:
[4464-33-9]
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