Geministatin A is a recently described depside antibiotic isolated from the fungus Austroacremonium gemini recovered from rotting wood in the wet tropics of northern Australia by Piggott, Chooi and collaborators, Australia in 2025. Geminstatin A is an analogue of aquastatin A with delta15,16 and delta18,19 double bonds which confer superior bioactivity. Geministatin A exhibits strong activity against B. subtilis and S. aureus antibiotic-susceptible and resistant strains with no significant mammalian cytotoxicity. Source: Austroacremonium gemini Molecular Formula: C38H52O12 Molecular Weight: 700.8 Appearance: White solid Solubility: Methanol, DMSO. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with methanol or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight:
700.8
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