ABIN-1, Recombinant, Human, aa94-530, His-Tag (TNIP1, TNFAIP3 Interacting Protein 1, HIV-1 Nef-interacting Protein, Nef-associated Factor 1, Naf1, Nip40-1, Virion-associated Nuclear Shuttling Protein, VAN, hVAN, KIAA0113, NAF1)

Product Overview

• Article Name: ABIN-1, Recombinant, Human, aa94-530, His-Tag (TNIP1, TNFAIP3 Interacting Protein 1, HIV-1 Nef-interacting Protein, Nef-associated Factor 1, Naf1, Nip40-1, Virion-associated Nuclear Shuttling Protein, VAN, hVAN, KIAA0113, NAF1)
• Biozol Catalog Number: USB-A0004-74H
• Supplier Catalog Number: A0004-74H
• Alternative Catalog Number: USB-A0004-74H-10,USB-A0004-74H-50
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

TNIP1 (TNFAIP3-interacting protein 1) has been shown to interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. In addition, interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. It may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. Recombinant corresponding to aa94-530 of human TNIP1 protein, fused to His-Tag at N-terminal, expressed in E.coli. Accession Number: NP_006049 Molecular Weight: ~51.8kD (458aa) confirmed by MALDI-TOF Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSNVTASPTA PACPSDKPAP VQKPPSSGTS SEFEVVTPEE QNSPESSSHA NAMALGPLPR EDGNLMLHLQ RLETTLSVCA EEPDHGQLFT HLGRMALEFN RLASKVHKNE QRTSILQTLC EQLRKENEAL KAKLDKGLEQ RDQAAERLRE ENLELKKLLM SNGNKEGASG RPGSPKMEGT GKKAVAGQQQ ASVTAGKVPE VVALGAAEKK VKMLEQQRSE LLEVNKQWDQ HFRSMKQQYE QKITELRQKL ADLQKQVTDL EAEREQKQRD FDRKLLLAKS KIEMEETDKE QLTAEAKELR QKVKYLQDQL SPLTRQREYQ EKEIQRLNKA LEEALSIQTP PSSPPTAFGS PEGAGALLRK QELVTQNELL KQQVKIFEED FQRERSDRER MNEEKEELKK QVEKLQAQVT LSNAQLKAFK DEEKAREALR QQKRKAKA Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 51.8
• NCBI: 006049
• UniProt: Q15025
• Purity: 80% (SDS-PAGE).
• Form: Supplied as a liquid in 20mM Tris-HCl, pH7.5, 5mM DTT, 200mM sodium chloride, 20% glycerol.