Adefovir is a more toxic analog of Tenofovir. Also, it is used with entecavir as similar efficacy in treating chronic hepatitis B. An acyclic phosphonate nucleotide analog of dAMP. Has anti-viral activity against HIV-1 and HBV by inhibiting reverse transcriptase and polymerase activity, respectively. Demonstrates improved antiviral activity when combined with other HBV drugs. Synonyms: P-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic Acid, 9-(2-Phosphonylmethoxyethyl)adenine, [[2-(6-Amino-9H-purin-9-yl)ethoxy] methyl]phosponic Acid, GS 0393, PMEA CAS No: 106941-25-7 Molecular Formula: C8H12N5O4P Molecular Weight: 273.19 Purity: 98% Appearance: White to off-white powder Melting Point: >282C (dec.) (lit) Loss on Drying: 1% Storage and Stability: Store at -20C. Product is stable for 6 months from time of receipt.
Molecular Weight:
273.19
CAS Number:
[106941-25-7]
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