In the extracellular space, ecto-5'-nucleotidase (CD73) dephosphorylates adenosine triphosphate (ATP) to produce adenosine. Adenosine has four receptors namely A1R, A2AR A2BR and A3R. Adenosine plays a key role in the osteogenic differentiation. A1R induces osteoclast differentiation and A2AR induces osteoblast differentiation. Adenosine has been used: as a supplement in embryonic type culture medium for in vitro osteogenic differentiation for evaluation of its effect on cell survival by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT assay) and cell proliferation by 3H-thymidine incorporation assay in multi drug resistant glioblastoma stem-like cells (GSCs), and as a standard in high performance liquid chromatography (HPLC). as a constituent in collagenase solution for the collagenase digestion of mice fat tissue. Synonyms: 9-beta-D-Ribofuranosyl-9H-purin-6-amine, 9-beta-D-Ribofuranosyladenine, Adenine Riboside, Adenocard, Adenocor, Adenogesic, Adenoscan, Adrekar, Boniton, D-Adenosine, 1-(6-Amino-9H-purin-9-yl)-1-deoxy-beta-D-ribofuranose, Myocol, NSC 7652 CAS No: 58-61-7 Molecular Formula: C10H13N5O4 Molecular Weight: 267.25 Purity (HPLC): 99% Appearance: White to off-white powder Melting Point: 230-234C Specific Optical Rotation: -68.0 to -73 Storage and Stability: Store at 4C. Stable for 12 months after receipt.
Molecular Weight:
267.25
CAS Number:
[58-61-7]
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