Naturally occurring amino acid, precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme. Antineoplastic (photosensitizer). 5-ALA is used in photodynamic therapy due to its properties as a photosensitizer, with applications in treatment of acne. 5-Aminolevulinic acid hydrochloride is used for visualisation of tumorous tissue in neurosurgical procedures enabling a reduction in the tumor residual volume and prolongation of progression-free survival in people with malignant gliomas. 5-ALA also has potential applications in diagnostic oncology in detection of bladder cancer Synonyms: 5-Amino-4-oxopentanoic Acid Hydrochloride, delta-Aminolevulinic Acid Hydrochloride, Aminolevulinic Acid Hydrochloride, 5-ALA HCl, Levulan CAS No: 5451-09-2 Free Base: 106-60-5 Molecular Formula: C5H10ClNO3 Molecular Weight: 167.59 Appearance: White to off-white powder Purity: 97% (HPLC) Melting Point: 145-155C (subl) Heavy Metals: 0.002% Iron (Fe): 0.002% Loss on Drying: 1% Residue on Ignition: 0.5% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
167.59
Purity:
97% (HPLC)
Form:
White to off-white powder
CAS Number:
[5451-09-2]
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