Antibiotic LL Z1640-2 (Antibiotic C292, Antibiotic L 783278), CAS [[66018-38-0]]

Product Overview

• Article Name: Antibiotic LL Z1640-2 (Antibiotic C292, Antibiotic L 783278), CAS [[66018-38-0]]
• Biozol Catalog Number: USB-A2297-23
• Supplier Catalog Number: A2297-23
• Alternative Catalog Number: USB-A2297-23-1,USB-A2297-23-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Antibiotic LL Z1640-2 a cis-enone resorcylic acid lactone first reported in 1978 and later rediscovered as an irreversible and highly selective TAK 1 inhibitor. TAK1 is a MAPKKK involved in the p38 signalling cascade for pro-inflammation signals such as cytokines. LL Z1640-2 effectively prevents inflammation in an animal models. Source: Antibiotic LL Z1640-2 CAS No: 66018-38-0 Purity: 95% by HPLC Molecular Formula: C19H22O7 Molecular Weight: ~362.4 Solubility: Ethanol, Methanol, DMF, DMSO. Limited water solubility. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 362.4
• Purity: 95% by HPLC
• Form: Supplied as a white solid.
• CAS Number: [66018-38-0]