Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignan. Apigenin is a 270Da flavonoid, which belongs to the flavone group of glycosides. It is synthesized by a wide variety of plants including cereals, grains, tea and oranges. Apigenin has been used as a calibration standard for the quantification of Hieracium pannosum Boiss, Juniperus sp, using high-performance liquid chromatography (HPLC) with Diode-Array Detection (DAD). It has been used to study effect on hormone secretion in the human adrenocortical H295R cells. Synonyms: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4,5,7-Trihydroxyflavone, Pelargidenon 1449 CAS No: 520-36-5 Molecular Formula: C15H10O5 Molecular Weight: 270.24 Appearance: Light yellow to dark yellow solid Purity: 97% Melting Point: >300C (lit.) Solubility: DMSO (Slightly), Methanol (Slightly, Heated) Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
270.24
Purity:
97%
Form:
Light yellow to dark yellow solid
CAS Number:
[520-36-5]
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