BCA-1, Recombinant, Human (B Cell Attracting Chemokine1, B Lymphocyte Chemoattractant, BLC, CXCL13, BLR1 Ligand)

Product Overview

• Article Name: BCA-1, Recombinant, Human (B Cell Attracting Chemokine1, B Lymphocyte Chemoattractant, BLC, CXCL13, BLR1 Ligand)
• Biozol Catalog Number: USB-B0395
• Supplier Catalog Number: B0395
• Alternative Catalog Number: USB-B0395-5,USB-B0395-20
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Human BCA-1 is a 10.3kD protein containing 85 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines. Amino Acid Sequence: VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP Biological Activity: Determined by its ability to chemoattract human B cells using a concentration range of 1-10ng/ml. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile acetic acid. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 10.3
• UniProt: O43927
• Purity: 98% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug)
• Form: Supplied as a lyophilized powder with no additives. Reconstitute with Acetic acid to a concentration of 0.1-1mg/ml. Do not vortex. Further dilute with PBS, 0.1% BSA or HSA.