A metallo-protease inhibitor. Inhibits aminopeptidase B, leucine aminopeptidase and leukotriene A4 hydrolase. Inhibits enkephalin degradation in cell preparations from brain. Does not inhibit carboxypeptidases. Sequence: [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine CAS No: 65391-42-6 Molecular Formula: C16H24N2O4.HCl Molecular Weight: 344.83 Appearance: White powder Purity: ~95% (HPLC) Melting Point: 213-215C Carbon, Anhydrous (%): 54.6-56.9% Nitrogen, Anhydrous (%): 8.0-8.3% Chloride, Anhydrous (%): 10.0-10.6% Moisture (Karl Fischer): 6% Solubility: Soluble in methanol and acetic acid. Colorless, clear to slightly hazy at 25mg/ml in water Storage and Stability: Lyophilized powder may be stored at 4C for short-term only. Reconstitute to nominal volume and store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. Protect from light.
Molecular Weight:
344.83
Purity:
98% (HPLC)
Form:
White powder
CAS Number:
[65391-42-6]
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