Bone Morphogenetic Protein 3b, Recombinant, Human (BMP3b, Growth Differentiation Factor 10, GDF10)
Biozol Catalog Number:
USB-B2553-11E
Supplier Catalog Number:
B2553-11E
Alternative Catalog Number:
USB-B2553-11E-100
Manufacturer:
US Biological
Category:
Molekularbiologie
GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Source: Recombinant GDF10 protein was expressed in E.coli and purified by using conventional chromatography techniques. Molecular Weight: 12.5kD(111aa) AA Sequence: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R Storage and Stability: For long-term storage, aliquot and store at -20C/-70C. Aliquots are stable for at least 6 months at -20C/-70C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
