Bone Morphogenetic Protein 7, Recombinant, Human, aa293-431 (BMP7, OP-1, Osteogenic Protein-1)
Biozol Catalog Number:
USB-B2553-34B
Supplier Catalog Number:
B2553-34B
Alternative Catalog Number:
USB-B2553-34B-100,USB-B2553-34B-500
Manufacturer:
US Biological
Category:
Molekularbiologie
Bone morphogenic protein-7 (BMP-7/OP-1) is a member of the transforming growth factor-beta (TGF-beta) superfamily. Like other members of the BMPs family, it plays a role in calcium regulation and bone homeostasis. BMPs have been also shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. BMP7 also has the potential for treatment of chronic kidney disease. Recombinant protein corresponding to aa293-431 from human BMP-7, fused to His-Tag, expressed in E. coli. Amino Acid Sequence: MSTGSKQRSQ NRSKTPKNQE ALRMANVAEN SSSDQRQACK KHELYVSFRD LGWQDWIIAP EGYAAYYCEG ECAFPLNSYM NATNHAIVQT LVHFINPETV PKPCCAPTQL NAISVLYFDD SSNVILKKYR NMVVRACGCH LEHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.