| Bryostatin 1 binds to and activates protein kinase C, but its biological effects differ greatly from those induced by other protein kinase C activators. Bryostatin 1 fails to mimic many effects caused by PMA and actually blocks some PMA-induced response in a variety of cells and tissues. Synonyms: NSC 339555, B705008K112, BRN 4349157, Bryostatin 1, protein kinase C activator, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl-(2E, 4E)-2,4-octadienoic acid ester CAS No: 83314-01-6 Molecular Formula: C47H68O17 Molecular Weight: 905.03 Purity (HPLC): 98% Appearance: Off-white solid Solubility: DMSO, Ethanol Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
