BTLA, Mouse IgG2a Fc Fusion Protein (B- and T-lymphocyte Attenuator, B- and T-lymphocyte-associated Protein, BTLA1, CD272, FLJ16065, MGC129743)

Product Overview

• Article Name: BTLA, Mouse IgG2a Fc Fusion Protein (B- and T-lymphocyte Attenuator, B- and T-lymphocyte-associated Protein, BTLA1, CD272, FLJ16065, MGC129743)
• Biozol Catalog Number: USB-B5001-61N
• Supplier Catalog Number: B5001-61N
• Alternative Catalog Number: USB-B5001-61N-25
• Manufacturer: US Biological
• Category: Molekularbiologie
• Application: ELISA

Product Description

Human CD272 (BTLA, B and T Lymphocyte Attenuator) is a member of the Immunoglobulin superfamily and has homology to CD152 (CTLA-4). Engagement of BTLA by its co receptor CD270 (HVEM, a TNF superfamily member) can down regulate activated T and B cell responses. BTLA levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines (1). Reactivity: CD272-muIg binds to recombinant HVEM-muIg. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• Purity: Purified by size exclusion.
• Form: Supplied as liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 150mM sodium chloride. No preservative added.