Calbindin 1, Recombinant Human (CAB27, CALB, CALB1, Calbindin 1 28kD, Calbindin D28, D28K, Vitamin D dependent calcium binding protein, Vitamin D dependent calcium binding protein avian type)
Biozol Catalog Number:
USB-C0113-01B
Supplier Catalog Number:
C0113-01B
Alternative Catalog Number:
USB-C0113-01B-100
Manufacturer:
US Biological
Category:
Molekularbiologie
Calbindin 1 is a calcium binding protein belonging to the troponin C superfamily. Calbindin is expressed in neural tissues. It plays an essential role in calcium regulation (including calcium transport and uptake, calcification of bone and teeth) and calcium related signalling in neurons and transiently in embryological development. This calbindin also has a role in protecting neurons from apoptotic cell death. Disregulation of this calbindin protein relates to epilepsy, amyotrophic lateral sclerosis, Huntingtons disease. Recombinant human Calbindin1 , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant human Calbindin1 , aa1-261, expressed in E. coli AA Sequence: MAESHLQSSL ITASQFFEIW LHFDADGSGY LEGKELQNLI QELQQARKKA GLELSPEMKT FVDQYGQRDD GKIGIVELAH VLPTEENFLL LFRCQQLKSC EEFMKTWRKY DTDHSGFIET EELKNFLKDL LEKANKTVDD TKLAEYTDLM LKLFDSNNDG KLELTEMARL LPVQENFLLK FQGIKMCGKE FNKAFELYDQ DGNGYIDENE LDALLKDLCE KNKQDLDINN ITTYKKNIMA LSDGGKLYRT DLALILCAGD N Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. For long-term storage, aliquot and store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
