CD37 is strongly expressed on the surface of human peripheral blood B cells and on B cells from the germinal center in lymph nodes. In the ontogeny of the B cells, CD37 appears at a late stage, but is not expressed on plasma cells. A main feature of CD37 is its high content of carbohydrate antigen 45%). CD37 has a very low but significant reactivity with T cells, granulocytes and monocytes. Applications: Suitable for use in Immunoprecipitation, ELISA, and Immunohistochemistry. Other applications have not been tested. Recommended Dilution: ELISA: 1:1000 Immunohistochemistry: Paraffin and frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Clonality:
Monoclonal
Clone Designation:
[1.BB.349]
Isotype:
IgG2b
Purity:
Purified by Protein A affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with Biotin.
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