CD49d (Antigen CD49d, CD49d Antigen, CDw49d, Alpha 4 Subunit of VLA-4 Receptor, Integrin alpha IV, Integrin alpha 4, IA4, ITGA4, LPAM23, MGC90518, Very Late Activation Protein 4 Receptor Alpha 4 Subunit, VLA4, VLA-4) (HRP), IgG1,
Biozol Catalog Number:
USB-C2404-46J-HRP
Supplier Catalog Number:
C2404-46J-HRP
Alternative Catalog Number:
USB-C2404-46J-HRP-100
Manufacturer:
US Biological
Host:
Mouse
Category:
Antikörper
Application:
IHC, IP
Immunogen:
Hyatt myeloma cell line.
CD49d, also known as integrin alpha 4, is a 150kD transmembrane glycoprotein, which may be cleaved to form 70kD and 80kD fragments. CD49d is expressed on a broad range of cells including lymphocytes, monocytes, eosinophils and thymocytes. The CD49d molecule forms heterodimers with either integrin Beta 1 (to form VLA-4) or beta 7 (to form alpha4 beta7), which mediate cell adhesion to VCAM-1 and fibronectin. Applications: Suitable for use in Immunohistochemistry (frozen), and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Clonality:
Monoclonal
Clone Designation:
[Bu49]
Isotype:
IgG1
Purity:
Purified by Protein G affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
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