CD49e (ITGA5, VLA-5, Integrin alpha 5 Chain) (FITC), Clone: [2Q969 NKI-SAM-1], Mouse, Monoclonal
Catalog Number:
USB-C2405-01B
- Images (0)
| Article Name: | CD49e (ITGA5, VLA-5, Integrin alpha 5 Chain) (FITC), Clone: [2Q969 NKI-SAM-1], Mouse, Monoclonal |
| Biozol Catalog Number: | USB-C2405-01B |
| Supplier Catalog Number: | C2405-01B |
| Alternative Catalog Number: | USB-C2405-01B-100 |
| Manufacturer: | US Biological |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC |
| Immunogen: | U937 cells |
| CD49e is a type I integral membrane glycoprotein, known as alpha5 integrin, VLA-5 alpha chain. It forms noncovalent heterodimer with integrin beta1 (CD29). CD49e contains two disulfide-linked subunits of 135 kD and 24 kD, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 5ul labels 10e6 cells in 100ul Optimal dilutions to be determined by researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
Product Guarantee and Expert Support
