CD54 (CD54 Antigen, BB2, Cell Surface Glycoprotein P3.58, Human Rhinovirus Receptor, Intercellular Adhesion Molecule 1, ICAM 1, ICAM1, ICAM-1, Major Group Rhinovirus Receptor, MALA-2, MyD10, P3.58), IgG1, Clone: [MEM-112], Mouse,
Biozol Catalog Number:
USB-C2409-11F
Supplier Catalog Number:
C2409-11F
Alternative Catalog Number:
USB-C2409-11F-100
Manufacturer:
US Biological
Host:
Mouse
Category:
Antikörper
Application:
FC, IP
Immunogen:
Raji Burkitts lymphoma cell line Raji
CD54 (ICAM-1) is a 90kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. Applications: Suitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
