Human Integrin alphaVbeta3 heterodimer isolated from placenta
CD61 (Glycoprotein IIIa, GPIIIa, Integrin beta3) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronection, von Willebrand factor and vitronectrin. Applications: Suitable for use in Flow Cytometry, Western Blot and Blocking studies. Other applications not tested. Recommended Dilutions: Western Blot: Reducing conditions Blocking: Blocks Integrin beta3-mediated adhesion to ECM proteins. Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.