Human Integrin alphaVbeta3 heterodimer isolated from placenta
CD61 (Glycoprotein IIIa, GPIIIa, Integrin beta3) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronection, von Willebrand factor and vitronectrin. Applications: Suitable for use in Flow Cytometry, Western Blot and Blocking studies. Other applications not tested. Recommended Dilutions: Western Blot: Reducing conditions Blocking: Blocks Integrin beta3-mediated adhesion to ECM proteins. Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.