CD61 (Integrin beta-3, Platelet Membrane Glycoprotein IIIa, GPIIIa, ITGB3, GP3A) (PE), Clone: [VI-PL2], Mouse, Monoclonal

Product Overview

• Article Name: CD61 (Integrin beta-3, Platelet Membrane Glycoprotein IIIa, GPIIIa, ITGB3, GP3A) (PE), Clone: [VI-PL2], Mouse, Monoclonal
• Biozol Catalog Number: USB-C2414-21M-PE
• Supplier Catalog Number: C2414-21M-PE
• Alternative Catalog Number: USB-C2414-21M-PE-100
• Manufacturer: US Biological
• Host: Mouse
• Category: Antikörper
• Application: FC

Product Description

CD61, known as integrin b3 or glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of integrin family that associates with platelet gpIIb (CD41) forming CD41/CD61 complex and associates with integrin aV (CD51) forming aV/b3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblast, macrophages and some tumor cells, involved in tumor metastasis and in adenovirus infection through binding to RGD motif ECM proteins. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 5ul/10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [VI-PL2]
• NCBI: 000212
• UniProt: P05106
• Purity: Purified by affinity chromatography.
• Form: Supplied as a liquid in PBS, pH 7.2, BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).