CD155 (Poliovirus Receptor, Nectin-like Protein 5, NECL-5, PVR, PVS), Rabbit
Biozol Catalog Number:
USB-C2548-85H
Supplier Catalog Number:
C2548-85H
Alternative Catalog Number:
USB-C2548-85H-50
Manufacturer:
US Biological
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, IHC
Immunogen:
Synthetic peptide corresponding to aa403-417 of human PVR (KLH).
The poliovirus receptor (PVR) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. PVR is involved in intercellular adhesion and its cytoplasmic domain may target endocytic vesicles to the microtubular network. The extracellular domain of PVR mediates cell attachment to the extracellular matrix molecule vitronectin, while its cytoplasmic domain interacts with the dynein light chain Tctex-1. PVR is a primate-restricted protein expressed during development in mesenchymal tissues and ventrally derived structures within the CNS. Its exact biological function remains to be determined, it is reported that PVR is aberrantly expressed in tumors of neuroectodermal origin. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Purity:
Purified by Protein G affinity chromatography.
Form:
Supplied as a liquid in PBS, 0.09% sodium azide.
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