CEBP gamma, DNA Binding Domain, Recombinant, Human, aa39-147, His-Tag (CCAAT Enhancer Binding Protein, gamma)
Catalog Number:
USB-C2589-94
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| Article Name: | CEBP gamma, DNA Binding Domain, Recombinant, Human, aa39-147, His-Tag (CCAAT Enhancer Binding Protein, gamma) |
| Biozol Catalog Number: | USB-C2589-94 |
| Supplier Catalog Number: | C2589-94 |
| Alternative Catalog Number: | USB-C2589-94-500 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| CCAAT/enhancer binding protein (C/EBP) gamma is a family of transcription factors all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP alpha, beta, gamma, delta, that form homodimers and/or form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein, a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBP gamma may cooperate with Fos to bind PRE-enhancer elements. The DNA binding domain of CEBP gamma (amino acid residues, 39-147) was produced in E .coli and purified by using conventional chromatography techniques. Molecular Weight: 16.5kD (146 amino acids) Sequence: MRGSHHHHHH/ GMASMTGGQQ/ MGRDLYDDDD/ KDRWGSMPGG/ GGKAVAPSKQ/ SKKSSPMDRN/ SDEYRQRRER/ NNMAVKKSRL/ KSKQKAQDTL/ QRVNQLKEEN/ ERLEAKIKLL/ TKELSVLKDL/ FLEHAHNLAD/ NVQSISTENT/ TADGDN Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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