Chromomycin A3, CAS [[7059-24-7]]

Product Overview

• Article Name: Chromomycin A3, CAS [[7059-24-7]]
• Biozol Catalog Number: USB-C5180
• Supplier Catalog Number: C5180
• Alternative Catalog Number: USB-C5180-1,USB-C5180-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Chromomycin A3 is the major component of the chromomycin complex of the aureolic acid class, isolated from several Streptomyces species and first reported in 1960. Chromomycin A3 exhibits a broad biological profile as an antibacterial, antifungal and antitumor agent. It binds reversibly to GC-specific DNA ligand in the minor groove which inhibits transcription, DNA gyrase and topoisomerase II. The intense UV spectrum and strong fluorescence makes chromomycin a useful stain for DNA. Synonyms: (1S)-1-C-[(2S,3S)-7-[[4-O-Acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-alpha-D-lyxo-hexopyranosyl)-beta-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl-(13)-O-2,6-dideoxy-beta-D-arabino-hexopyranosyl-(13)-2,6-dideoxy-beta-D-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-D-threo-2-pentulose, Aburamycin B, Antibiotic B 599, CMA3, NSC 58514, Toyomycin, 3D-O-(4-O-Acetyl-2,6-dideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-7-methyl-olivomycin D CAS No: 7059-24-7 Molecular Formula: C57H82O26 Molecular Weight: 1183.25 Appearance: Yellow powder Purity: 98% (HPLC) Melting Point: xxxC Solubility: xxx Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Source: Chromomycin A3 from Stretomyces griseus. Molecular Weight: ~1183.3 Solubility: Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 1183.25
• Purity: 98% (HPLC)
• Form: Yellow powder
• CAS Number: [7059-24-7]