COMMD1, aa1-190, Recombinant, Human (C2orf5, COMM Domain-containing Protein 1, MGC27155, MURR1, Protein Murr1)
Biozol Catalog Number:
USB-C7847-51
Supplier Catalog Number:
C7847-51
Alternative Catalog Number:
USB-C7847-51-50
Manufacturer:
US Biological
Category:
Molekularbiologie
COMMD1, also known as copper metabolism MURR1 domain-containing protein 1, is a 190aa protein responsible for inhibition of TNF-induced NFkB p50 and has a suggested role in facilitation of biliary copper excretion within hepatocytes. High expression is found in liver tissue, with lower expressions in lung, heart, kidney and brain tissue. This protein interacts directly with COMMD6 and ATP7B, and indirectly with IkB-B and COMMD7. Source: Recombinant corresponding to aa1-190 of human COMMD1 6x his tagged, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAAGELEGGK PLSGLLNALA QDTFHGYPGI TEELLRSQLY PEVPPEEFRP FLAKMRGILK SIASADMDFNQLEAFLTAQT KKQGGITSDQ AAVISKFWKS HKTKIRESLM NQSRWNSGLR GLSWRVDGKS QSRHSAQIHT PVAIIELELG KYGQESEFLC LEFDEVKVNQ ILKTLSEVEE SISTLISQPN Molecular Weight: 23.3kD (210aa), confirmed by MALDI-TOF Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
