Complement Factor B, Ba Fragment (APC), IgG1, Clone: [014III-33.2.4.3], Mouse, Monoclonal
Biozol Catalog Number:
USB-C7850-60D-APC
Supplier Catalog Number:
C7850-60D-APC
Alternative Catalog Number:
USB-C7850-60D-APC-100
Manufacturer:
US Biological
Host:
Mouse
Category:
Antikörper
Application:
FC, FLISA, IHC, WB
Immunogen:
Purified human complement factor B
C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kDa Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. Applications: Suitable for use in FLISA, Flow Cytometry, Functional Assays, Immunohistochemistry and Western Blot. Other applications have not been tested. Recommended Dilution: Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher. Immunohistochemistry Positive Control: Kidney from post streptococcal glomerulonephritis patients Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
