Complement Factor H-Related Protein 1 (FHR1), Sheep
Catalog Number:
USB-C7850-86
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| Article Name: | Complement Factor H-Related Protein 1 (FHR1), Sheep |
| Biozol Catalog Number: | USB-C7850-86 |
| Supplier Catalog Number: | C7850-86 |
| Alternative Catalog Number: | USB-C7850-86-100 |
| Manufacturer: | US Biological |
| Host: | Sheep |
| Category: | Antikörper |
| Application: | ELISA, IP, WB |
| Immunogen: | Recombinant protein corresponding to Glu19-Ala328 from human Complement Factor H-Related Protein 1 (FHR1), expressed in NSO cells (AAH16755). |
| Complement Factor H-related protein 1 is a 43kD, secreted member of the factor H family of glycoproteins. It is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37kD and 43kD). Mature human FHR1 is 312aa in length. It contains five, ~60aa SCRs (short consensus repeats/CCPs/SUSHI repeats) that basically constitute the entire molecule. FHR1 may play a role in lipoprotein complexes that bind PMNs to LPS. There is no reported rodent counterpart to FHR1. Over aa 19-143 of the FHR1 precursor, human FHR2 and FHR5 show 98% and 86% aa identity, respectively. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Western Blot: 0.1ug/ml with recombinant Complement Factor H-Related Protein 1 Immunoprecipitation: 25ug/ml. Used to immunoprecipitate recombinant human FHR1 from conditioned media of transfected NSO cells. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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