C-Reactive Protein, Mouse, Control Peptide (CRP, MGC88244, PTX 1, PTX1)
Biozol Catalog Number:
USB-C7907-16E
Supplier Catalog Number:
C7907-16E
Alternative Catalog Number:
USB-C7907-16E-100
Manufacturer:
US Biological
Category:
Molekularbiologie
Application:
ELISA
Pentraxins family of proteins acquired the name from their ability to form pentameric (or decameric) structures formed by non-covalent interactions. C-reactive protein (CRP or PTX1, mature chain 206 aa, chromosome 1q21-23) nonglycosylated, ~24kD monomer and ~118kD pentamer) is a ubiquitous protein found in both vertebrates and invertebrates. Originally CRP was defined as a substance, observed in the plasma of patients with acute infections, that reacted with the C polysaccharide of the pneumococcus. It is one of the plasma proteins that are called acute phase reactants because of a pronounced rise in concentration after tissue injury or inflammation, in the case of CRP the rise may be 1000-fold or more. CRP is composed of 5 identical, 21,500-molecular weight subunits. It is detectable on the surface of about 4% of normal peripheral blood lymphocytes. Acute phase reactant CRP is produced in the liver, those cells produce CRP detectable on lymphocytes. Source: A mixture of peptides from mouse CRP (1 peptide near the N-terminus and 1 peptide from C-terminus) were coupled to KLH. The two free peptides can be used for ELISA or antibody blocking. Applications: Suitable for use in ELISA and Antibody Blocking. Not suitable for Western Blot due to low MW <3kD. Other applications not tested. Recommended Dilution: Elisa and Antibody Blocking: 5-10ug per 1ug C7907-15D (affinity purified antibody). Optimal dilutions to be determined by the researcher Storage and Stability: May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Purity:
Purified
Form:
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
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