CUGBP2, Control Peptide (CUGBP Elav-like Family Member 2, CELF-2, Bruno-like Protein 3, CUG Triplet Repeat RNA-binding Protein 2, CUG-BP2, CUG-BP- and ETR-3-like Factor 2, ELAV-type RNA-binding Protein 3, ETR-3, Neuroblastoma Apop

Product Overview

• Article Name: CUGBP2, Control Peptide (CUGBP Elav-like Family Member 2, CELF-2, Bruno-like Protein 3, CUG Triplet Repeat RNA-binding Protein 2, CUG-BP2, CUG-BP- and ETR-3-like Factor 2, ELAV-type RNA-binding Protein 3, ETR-3, Neuroblastoma Apop
• Biozol Catalog Number: USB-C7948-50G
• Supplier Catalog Number: C7948-50G
• Alternative Catalog Number: USB-C7948-50G-100
• Manufacturer: US Biological
• Category: Molekularbiologie
• Application: ELISA

Product Description

Control peptide for C7948-50F, polyclonal antibody to CUGBP2. RNA editing is an important mechanism for regulating genetic plasticity through the generation of alternative protein products from a single structural gene. There are two types of substitutional RNA exist in mammals, namely A-to-I and C-to-U RNA editing. The best-characterized example of C-to-U RNA editing involves the nuclear transcript encoding intestinal apolipoprotein B (apo B)). Apo B RNA editing changes a CAA to a UAA stop codon, generating a truncated protein, apoB48. The functional complex includes a minimal core composed of apobec-1 and ACF, that function as an adaptor protein by binding both the deaminase and the RNA substrate. The RNA binding proteins also include CUGBP2 which along with Apobec-1 binds to the consensus binding sequence UUUN (A/U) U, present in c-myc, VEGF and Cyclooxygenase-2 (COX2). Source: Synthetic peptide corresponding to 18aa of human CUGBP2, C-terminal. Molecular Weight: ~3kD Applications: Suitable for use in ELISA. Not suitable for Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 3
• Purity: Purified
• Form: Supplied as a lyophilized pwder from PBS, pH7.5.