Cystatin A, Recombinant, Human, aa1-98, His-Tag (Stefin A, Cystatin-A, Cystatin-AS, Stefin-A, CSTA, STF1, STFA)
Biozol Catalog Number:
USB-C8949-18D
Supplier Catalog Number:
C8949-18D
Alternative Catalog Number:
USB-C8949-18D-100,USB-C8949-18D-500
Manufacturer:
US Biological
Category:
Molekularbiologie
CSTA, also known as Stefin A, is thiol protease inhibitors that form complexes with papain and the cathepsins B, H and L. The protein is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. CSTA is thought to be a tumor suppressor, since an inverse correlation seems to exist between the level of CSTA and tumor progression, in several malignancies. Source: Recombinant corresponding to aa1-98 from human CSTA, fused to His-tag at N-terminus expressed in E.coli. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MIPGGLSEAK PATPEIQEIV DKVKPQLEEK TNETYGKLEA VQYKTQVVAG TNYYIKVRAG DNKYMHLKVF KSLPGQNEDL VLTGYQVDKN KDDELTGF Molecular Weight: ~13.1kD (118aa), confirmed by MALDI-TOF Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
