N-Desmethyl-4-hydroxytamoxifen-ethyl-d5 (1:1 E/Z Mixture) (E/Z Endoxifen-d5), CAS [[1584173-54-5]]

Product Overview

• Article Name: N-Desmethyl-4-hydroxytamoxifen-ethyl-d5 (1:1 E/Z Mixture) (E/Z Endoxifen-d5), CAS [[1584173-54-5]]
• Biozol Catalog Number: USB-D3220-88P
• Supplier Catalog Number: D3220-88P
• Alternative Catalog Number: USB-D3220-88P-1
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A novel active labeled metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line. Synonyms: E/Z Endoxifen-d5, 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl-d5]phenol CAS No: 1584173-54-5 Unlabeled: 110025-28-0 Molecular Formula: C25H22D5NO2 Molecular Weight: 378.52 Purity: 96% Appearance: Pale brown to pale orange solid Solubility: Chloroform (Slightly), Methanol (Slightly) Method for Determining Identity: Proton NMR Spectroscopic and Mass Spectrometric Analysis TLC Conditions: SiO2: Dichloromethane: Methanol: NH4OH, 9:1:0.1: Visualized with UV and AMCS, Single spot, Rf=0.3. Elemental Analysis: Calculated: %C: 79.33, %H: 7.19, %N: 3.70 Normalized Intensisty: d0=0.05%, d1=0.08%, d2=0.00%, d3=0.01%, d4=1.86%, d5=98.00% Melting Point: 74-78C (lit) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C for 6 months after time of receipt.

Product Properties

• Molecular Weight: 378.52
• CAS Number: [1584173-54-5]