| A steroid extracted from the adrenal cortex. 11-Dehydrocorticosterone is a precursor to corticosterone converted by 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) which plays a role in glucocorticoid-induced insulin resistance. Synonyms: 4-Pregnen-21-ol-3, 11, 20-trione, 11-Oxo-11-deoxycorticosterone, 11-Oxocorticosterone, 17-(1-keto-2-Hydroxyethyl)-delta4-androsten-3,11-dione, 4-Pregnen-21-ol-3,11,20-trione, 11-Dehydro-corticosterone, Dehydrocorticosterone, Kendalls compound A, NSC-9702, delta4-Pregnen-21-ol-3,11,20-trione, delta4-Pregnene-21-ol-3,11,20-trione CAS No: 72-23-1 Molecular Formula: C21H28O4 Molecular Weight: 344.44 Purity (HPLC): 90% Appearance: White to pale yellow solid Solubility: Chloroform (Slightly), Dioxane (Slightly), Methanol (Slightly) TLC Conditions: SiO2, Dichloromethane: Methanol=9,1, Visualized with UV and AMCS, Single spot, Rf=0.60 Melting Point: 177-179°C Specific Rotation (c=0.3, Dioxane): +260° Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C for 6 months after time of receipt. Light sensitive. |
