| Diethylstilbestrol is a synthetic estrogen with carcinogenic properties. Causes renal clear-cell carcinoma in Syrian hamster. In humans it causes increased risk of breast cancer, clear cell adenocarcinoma (CCA) of the vagina and cervix, and reproductive anomalies. Used in the treatment of prostate cancer to block the production of testosterone. Synonyms: 4,4-[(1E)-1,2-Diethyl-1,2-ethenediyl]bisphenol, (E)-3,4-Bis(4-hydroxyphenyl)-3-hexene, DES, (E)-4,4-(1,2-Diethyl-1,2-ethenediyl)bisphenol, (E)-Diethylstilbestrol, 4,4-Dihydroxy-alpha,beta-diethylstilbene, 4,4-Dihydroxydiethylstilbene, Agostilben, Antigestil, Bertrol, Bio-des, Bufon, Comestrol, Cyren, Cyren A CAS No: 56-53-1 Molecular Formula: C18H20O2 Molecular Weight: 268.35 Appearance: White to off-white powder Purity: 98% Method for Determining Identity: Proton NMR Spectroscopic Analysis and Mass Spectrometric Analysis TLC Conditions: SiO2: Hexane: Ethyl acetate =1:1, Visualized with UV and AMCS, Single spot=0.7 Melting Point: 169-171C Solubility: DMF (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Stability Isomerizes rapidly in Benzene, Chloroform, and Ether. Keep Shielded from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
