DNAJB2, Recombinant, Human, aa1-277, His-Tag (DnaJ Homolog Subfamily B Member 2, DnaJ Protein Homolog 1 Heat Shock 40kD Protein 3 Heat Shock Protein J1, HSJ-1, HSJ1, HSPF3)
Biozol Catalog Number:
USB-D4015-08A2
Supplier Catalog Number:
D4015-08A2
Alternative Catalog Number:
USB-D4015-08A2-50,USB-D4015-08A2-250
Manufacturer:
US Biological
Category:
Molekularbiologie
DnaJB2, also known as HSJ1 or HSPF3, is belongs to the DnaJ family. It is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The DnaJ proteins play a critical role in the HSP70 chaperone machine by interacting with HSP70 to stimulate ATP hydrolysis. DnaJB2 is important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. Recombinant protein corresponding to aa1-277 of human DNAJB2 protein, fused to His-Tag at N-terminus, expressed in E.coli. Swiss/Uniprot Accession: P25686 Molecular Weight: ~33kD (300aa) confirmed by MALDI-TOF Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMASYYEI LDVPRSASAD DIKKAYRRKA LQWHPDKNPD NKEFAEKKFK EVAEAYEVLS DKHKREIYDR YGREGLTGTG TGPSRAEAGS GGPGFTFTFR SPEEVFREFF GSGDPFAELF DDLGPFSELQ NRGSRHSGPF FTFSSSFPGH SDFSSSSFSF SPGAGAFRSV STSTTFVQGR RITTRRIMEN GQERVEVEED GQLKSVTING VPDDLALGLE LSRREQQPSV TSRSGGTQVQ QTPASCPLDS DLSEDEDLQL AMAYSLSEME AAGKKPADVF Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.