DRAK2, CT, Blocking Peptide (DAP Kinase-related Apoptosis-inducing Protein Kinase 2)
Biozol Catalog Number:
USB-D9335P
Supplier Catalog Number:
D9335P
Alternative Catalog Number:
USB-D9335P-50
Manufacturer:
US Biological
Category:
Molekularbiologie
Peptide corresponding to amino acids 351 to 365 of human DRAK2 (1). Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases) (1). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues (1).
Purity:
Purified
Form:
Supplied as a liquid in PBS, pH 7.2, 0.1% BSA, 0.02% sodium azide.
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