Dysadherin, Control Peptide (FXYD Domain Containing Ion Transport Regulator 5, FXYD5RIC, HSPC113, IWU1, KCT1)
Biozol Catalog Number:
USB-D9904-50A
Supplier Catalog Number:
D9904-50A
Alternative Catalog Number:
USB-D9904-50A-1
Manufacturer:
US Biological
Category:
Molekularbiologie
Application:
WB
Synthetic (linear) peptide: GKCRQLSRLCRNHCR (Human). Corresponding antibody D9904-50 recognizes human Dysadherin. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Application(s): Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: Ab (D9904-50): 0.5-1.5ug/ml, ~40kD band seen in Jurkat lysate. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4C for short-term only. Stable for 12 months at -20C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Purity:
95+% HPLC, Mass Spec
Form:
Supplied as a white to off-white lyophilized powder.
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