Epidermal Growth Factor, Recombinant, Human, aa971-1023 (EGF, Urogastrone)
Catalog Number:
USB-E3374-03D
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| Article Name: | Epidermal Growth Factor, Recombinant, Human, aa971-1023 (EGF, Urogastrone) |
| Biozol Catalog Number: | USB-E3374-03D |
| Supplier Catalog Number: | E3374-03D |
| Alternative Catalog Number: | USB-E3374-03D-100,USB-E3374-03D-500 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| Recombinant human epidermal growth factor(EGF) is a 6.3kD globular protein containing 54 amino acids residues, including 3 intra-molecular disulfide bonds. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. Recombinant protein corresponding to aa971-1023 from human EGF, expressed in E. coli Amino Acid Sequence: MNSDSECPLS HDGYCLHDGV CMYIEALDKY ACNCVVGYIG ERCQYRDLKW WELR Biological Activity: Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is less or equal to 0.1ng/ml. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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