FADD, Recombinant Human, His-Tag, aa1-208 (Fas-associated protein with death domain)

Catalog Number: USB-F0019-53F
Article Name: FADD, Recombinant Human, His-Tag, aa1-208 (Fas-associated protein with death domain)
Biozol Catalog Number: USB-F0019-53F
Supplier Catalog Number: F0019-53F
Alternative Catalog Number: USB-F0019-53F-50
Manufacturer: US Biological
Category: Molekularbiologie
FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules. Recombinant FADD protein was expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant corresponding to human FADD, his-tagged, expressed in E. coli. AA sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS Storage and Stability: May be stored at 4C for short-term only. For long-term storage, aliquot and store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 27.4
Purity: ~95% (SDS-PAGE) Purified by immunoaffinity chromatography.
Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.