Formyl Peptide Receptor-like 1, Control Peptide, Rabbit
Biozol Catalog Number:
USB-F6010-10A1
Supplier Catalog Number:
F6010-10A1
Alternative Catalog Number:
USB-F6010-10A1-1
Manufacturer:
US Biological
Host:
Rabbit
Category:
Molekularbiologie
Application:
FC, IF, WB
Immunogen:
Synthetic peptide (ASWGGTPEERLKC) corresponding to residues of the 2nd extracellular loop of human FPRL1, conjugated to KLH.
FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries. Sequence: The sequence ASWGGTPEERLKC corresponds to amino acids 181-192 of FPRL1, plus one added Cysteine residue. Applications: Control Peptide for anti-FPRL1, CatF6010-10A Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Purity:
95+% HPLC, Mass Spec
Form:
Supplied as a white to off-white lyophilized powder.
* VAT and and shipping costs not included. Errors and price changes excepted
