GADD45G, Recombinant, Human (Growth Arrest and DNA Damage-inducible 45, gamma, CR6, DDIT2)
Biozol Catalog Number:
USB-G1017-21C
Supplier Catalog Number:
G1017-21C
Alternative Catalog Number:
USB-G1017-21C-100,USB-G1017-21C-500
Manufacturer:
US Biological
Category:
Molekularbiologie
Application:
WB
GADD45G is a member of GADD45 family (GADD45 alpha, beta, and gamma) that are nuclear proteins to interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. Source: Recombinant corresponding to aa1-159 of human GADD45G expressed in E .coli. Amino Acid Sequence: MTLEEVRGQD TVPESTARMQ GAGKALHELL LSAQRQGCLT AGVYESAKVL NVDPDNVTFC VLAAGEEDEG DIALQIHFTL IQAFCCENDI DIVRVGDVQR LAAIVGAGEE AGAPGDLHCI LISNPNEDAW KDPALEKLSL FCEESRSVND WVPSITLPE Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 3ug/ul 15% SDS-PAGE, ~17.1kD. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
