GLUT3 (Solute Carrier Family 2, Facilitated Glucose Transporter Member 3, Glucose Transporter Type 3, Brain, GLUT-3, SLC2A3), IgG2b, Clone: [11C103], Mouse, Monoclonal
Biozol Catalog Number:
USB-G3900-21A
Supplier Catalog Number:
G3900-21A
Alternative Catalog Number:
USB-G3900-21A-100
Manufacturer:
US Biological
Host:
Mouse
Category:
Antikörper
Application:
FC
Immunogen:
Recombinant protein corresponding to human GLUT3. Epitope: Extracellular.
Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes 7 proteins (Glut-1 to Glut-13, Mol. Wt. 40-80kD) and Sodium glucose co-transporter-1 (SGLT-1, 662aa, ~75kD). Individual member of this family have identical predicted secondary structures with 12 transmembrane domains. Both N and C-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue-specific targeting. Glut isoforms differ in their tissue expression, substrate specificity and kinetic characteristics. GLUT3 (human 496aa, mouse 493aa) is the main transporter in neurons, whereas Glut-4 is primarily expressed in muscle and adipose tissue and regulated by insulin. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: ~10ug/ml labels 10e6 cells. Perform the antibody binding in small volume of ~200ul. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality:
Monoclonal
Clone Designation:
[11C103]
Isotype:
IgG2b
Purity:
Purified by Protein A/G affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.5. No preservative added.
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