Growth and Differentiation Factor 5, aa382-501, Recombinant, Human (GDF5)
Biozol Catalog Number:
USB-G8989-45B
Supplier Catalog Number:
G8989-45B
Alternative Catalog Number:
USB-G8989-45B-100,USB-G8989-45B-500
Manufacturer:
US Biological
Category:
Molekularbiologie
Growth differentiation factor 5(GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinsons disease. GDF-5, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E. coli. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAPLATRQGK RPSKNLKARC SRKALHVNFK DMGWDDWIIA PLEYEAFHCE GLCEFPLRSH LEPTNHAVIQ TLMNSMDPES TPPTCCVPTR LSPISILFID SANNVVYKQY EDMVVESCGC R Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
