Heat Shock Protein 70 Interacting Protein, Recombinant, Human (Heat Shock Protein Binding Protein 1, Hsp70 Binding Protein 1, HSPBP1, HSPBP, FES1, Hsp70 Binding Protein 2, HspBP2, Hsp70-interacting Protein 1, Hsp70-interacting Pro

Catalog Number: USB-H1834-41H
Article Name: Heat Shock Protein 70 Interacting Protein, Recombinant, Human (Heat Shock Protein Binding Protein 1, Hsp70 Binding Protein 1, HSPBP1, HSPBP, FES1, Hsp70 Binding Protein 2, HspBP2, Hsp70-interacting Protein 1, Hsp70-interacting Pro
Biozol Catalog Number: USB-H1834-41H
Supplier Catalog Number: H1834-41H
Alternative Catalog Number: USB-H1834-41H-50
Manufacturer: US Biological
Category: Molekularbiologie
Application: WB
Hsp70-binding protein 1, also known as HSPBP1, belongs to a family of eukaryotic proteins identified as nucleotide exchange factors for HSP 70, which exhibit varying degrees of compartment and species specificity. It is localized primarily in cytoplasm and nucleus but is also found extracellularly. HspBP1 binds to HSP 70, inhibits its activity and promotes dissociation of nucleotides from the HSP 70 ATPase domain. It is mainly expressed in heart and skeletal muscle. Recombinant human HSPBP1, fused to His-tag at N-terminus, was expressed in E. coli. Source: Recombinant corresponding to aa1-362 of human HSPBP1 6x His tagged expressed in E. coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSDEGSRGSR LPLALPPASQ GCSSGGGGGG GGGSSAGGSG NSRPPRNLQG LLQMAITAGS EEPDPPPEPM SEERRQWLQE AMSAAFRGQR EEVEQMKSCL RVLSQPMPPT AGEAEQAADQ QEREGALELL ADLCENMDNA ADFCQLSGMH LLVGRYLEAG AAGLRWRAAQ LIGTCSQNVA AIQEQVLGLG ALRKLLRLLD RDACDTVRVK ALFAISCLVR EQEAGLLQFL RLDGFSVLMR AMQQQVQKLK VKSAFLLQNL LVGHPEHKGT LCSMGMVQQL VALVRTEHSP FHEHVLGALC SLVTDFPQGV RECREPELGL EELLRHRCQL LQQHEEYQEE LEFCEKLLQT CFSSPADDSM DR Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight: 41.6
NCBI: 01236
Purity: ~ 95% (SDS-PAGE)
Form: Supplied as a liquid in 20mM Tris HCl, pH 8.0, 2mM EDTA, 0.1M NaCl, 2mM DTT, 30% glycerol.