Heme Oxygenase 2, Recombinant, Human (HO-2, HMOX2)
Biozol Catalog Number:
USB-H1847-82B
Supplier Catalog Number:
H1847-82B
Alternative Catalog Number:
USB-H1847-82B-100
Manufacturer:
US Biological
Category:
Molekularbiologie
Application:
WB
HMOX2 is microsomal enzyme that cleave heme ring at the alpha methane bridge to produce the antioxidant biliverdin, inorganic iron and carbon monoxide. Biliverdin is subsequently converted to bilirubin by bilibverdin reductase. This protein appears to be constitutively expressed in mammalian tissues. HMOX2 is involved in the production of carbon monoxide (CO) in brain, where CO is thought to act as a neurotransmitter. Recombinant HMOX2 protein was expressed in E.coli and purified by using conventional chromatography techniques. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Endotoxin: 1EU/1ug (LAL). Amino Acid Sequence: MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRK Molecular Weight: 30.5kD (264aa) Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
