o-Hydroxy Atorvastatin Lactone, CAS [[163217-74-1]]
Biozol Catalog Number:
USB-H9036-50
Supplier Catalog Number:
H9036-50
Alternative Catalog Number:
USB-H9036-50-1,USB-H9036-50-2,USB-H9036-50-5
Manufacturer:
US Biological
Category:
Biochemikalien
A metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Synonyms: 5-(4-Fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide, Atorvastatin 2-Hydroxy Lactone CAS No: 163217-74-1 Molecular Formula: C33H33FN2O5 Molecular Weight: 556.62 Appearance: Off-white to pale yellow solid Purity: ~90% Melting Point: 96-102C Method for Determining Identity: Proton NMR (CD3OD) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: SiO2, Dichloromethane: Methanol=9:1, Visualized with UV and AMCS, Rf=0.60. Ethyl Acetate: As Reported Solubility: Chloroform (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
556.62
Purity:
~90%
Form:
Off-white to pale yellow solid
CAS Number:
[163217-74-1]
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