Interferon alpha 2b, Recombinant, Human (IFNa2, IFNa2b), aa24-188
Biozol Catalog Number:
USB-I7661-75B
Supplier Catalog Number:
I7661-75B
Alternative Catalog Number:
USB-I7661-75B-100,USB-I7661-75B-500
Manufacturer:
US Biological
Category:
Molekularbiologie
Interferon induces a variety of effects on target cells including antiviral, antiproliferative, and immunomodulatory activities. Interferon a-2b can either inhibit or enhance immune cell activity within the tightly regulated microenvironment of inflammation, depending upon the concentration of the cytokine and the activation stage of the cell. Interferon a-2b was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Recombinant protein corresponding to aa24-188 of human IFNA2 expressed in E. coli (NP_000596). Amino Acid Sequence: MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.