Interferon Regulatory Factor 1, Recombinant, Human (IRF1)
Biozol Catalog Number:
USB-I7662-81
Supplier Catalog Number:
I7662-81
Alternative Catalog Number:
USB-I7662-81-100,USB-I7662-81-500
Manufacturer:
US Biological
Category:
Molekularbiologie
IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. Recombinant human IRF1 was expressed in E. coli and purified by using conventional chromatography techniques. Molecular Weight: 15kD (114 amino acids) Sequences: MGSSHHHHHH/ SSGLVPRGSH/ MPITRMRMRP/ WLEMQINSNQ/ IPGLIWINKE/ EMIFQIPWKH/ AAKHGWDINK/ DACLFRSWAI/ HTGRYKAGEK/ EPDPKTWKAN/ FRCAMNSLPD/ IEEVKDQSRN/ KGSSAVRVYR/ MLPP Storage and Stability: May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
15
Purity:
90% by SDS-PAGE
Form:
Supplied as a liquid in 20mM Tris, pH 8.0, 10% glycerol
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