IL1B, ID (Interleukin-1 beta, IL-1 beta, Catabolin, IL1F2), Rabbit
Catalog Number:
USB-I7663-20B
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| Article Name: | IL1B, ID (Interleukin-1 beta, IL-1 beta, Catabolin, IL1F2), Rabbit |
| Biozol Catalog Number: | USB-I7663-20B |
| Supplier Catalog Number: | I7663-20B |
| Alternative Catalog Number: | USB-I7663-20B-200 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, FC, IHC, WB |
| Immunogen: | KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 148-174 in the central region of human IL1B, UniProt Accession NP_000567.1, P01584. Species sequence homology: rabbit, monkey |
| IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. Applications: Suitable for use in ELISA, Western Blot, Indirect Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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