Interleukin 1 Receptor Antagonist, Recombinant, Human (IL-1RA)
Biozol Catalog Number:
USB-I7663-25N3
Supplier Catalog Number:
I7663-25N3
Alternative Catalog Number:
USB-I7663-25N3-100,USB-I7663-25N3-500
Manufacturer:
US Biological
Category:
Molekularbiologie
One of the most potent pro-inflammatory mediators is the early-acting cytokine interleukin-1 (IL-1), whose actions are regulated by the structurally related IL-1 receptor antagonist (IL-1 RA). IL-1 RA is a competitive IL-1 inhibitor and a powerful anti-inflammatory agent. Also, Several autoimmune and inflammatory diseases have been associated with an allelic polymorphism of the IL-1 RA gene. Recombinant human IL-1 RA was expressed in E. coli and consists of 153 amino acids. Amino Acid Sequence: MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. For long-term storage, aliquot and store at -20C. Aliquots are stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
17.2
Purity:
95% by SDS-PAGE. Purified by using conventional chromatography techniques.
Form:
Supplied as a liquid in PBS, pH 7.4.
* VAT and and shipping costs not included. Errors and price changes excepted